论文部分内容阅读
氨氯地平为二氢吡啶类钙离子拮抗剂,具有血管选择性,在扩张血管的同时对心脏的传导和收缩力均无影响。本品治疗高血压的作用机制与其扩张全身小动脉从而降低外周血管阻力的作用有关。对缺血性心脏病,本品一方面通过扩张全身小动脉,降低心脏后负荷和心肌耗氧量;另一方面,还使冠脉血流量增加,改善心肌供氧,通过纠正心肌耗氧和供氧的平衡而控制缺血性心脏病发作[1]。
Amlodipine dihydropyridine calcium antagonists, with vascular selectivity in the dilation of blood vessels at the same time the conduction and contractility of the heart had no effect. The role of this product in the treatment of hypertension and its expansion of the entire arterioles and thus reduce the role of peripheral vascular resistance. On ischemic heart disease, the goods on the one hand through the expansion of the whole body arterioles, reduce cardiac afterload and myocardial oxygen consumption; the other hand, also increased coronary blood flow, improve myocardial oxygen supply, by correcting myocardial oxygen consumption and Oxygen balance and control of ischemic heart attack [1].