【摘 要】
：
血红素加氧酶(heme oxygenase,HO)是血红素代谢的限速酶,可分解血红素生成一氧化碳(CO)、胆红素和游离铁。作为一种抗氧化防御酶在大多数组织内呈低水平表达,当被伤害性刺激
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血红素加氧酶(heme oxygenase,HO)是血红素代谢的限速酶,可分解血红素生成一氧化碳(CO)、胆红素和游离铁。作为一种抗氧化防御酶在大多数组织内呈低水平表达,当被伤害性刺激诱导时产生高水平表达。HO有3种不同的亚型:HO-1、HO-2和HO-3。既往研究表明HO-1具有抗炎、抗氧化、抗凋
Heme oxygenase (HO) is a rate-limiting enzyme in heme metabolism that decomposes heme to form carbon monoxide (CO), bilirubin, and free iron. As an antioxidant defense enzyme in most tissues was low-level expression, when induced by noxious stimulation to produce high-level expression. There are 3 different subtypes of HO: HO-1, HO-2 and HO-3. Previous studies have shown that HO-1 has anti-inflammatory, anti-oxidation, anti-withering
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