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synucleins是脊椎动物中高度保守的小分子量蛋白家族 ,主要在神经元表达 ,在突触前末梢尤为丰富。SNCG(synucleingamma;spersyn ;breastcancer specificprotein 1)是该家族的第三个成员 ,在脑中广泛表达 ,其表达异常与神经退行性病变和细胞恶变都有一定的相关性。它在神经元胞
Synucleins are highly conserved small molecular weight protein families in vertebrates that are predominantly expressed in neurons and particularly abundant in presynaptic terminals. SNCG (synucleinamma; spersyn; breastcancer specific protein 1) is the third member of this family and is widely expressed in the brain. The abnormal expression of SNCG is associated with both neurodegenerative diseases and cell malignant transformation. It’s in neurons