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酵母菌对口腔粘膜细胞的粘附是其致病性的主要特征之一。艾滋病患者细胞免疫功能进行性衰退易致机会性感染,其中80％以上由白念珠菌引起。作者利用放射计量技术将从HIV(+)患者颊粘膜分离出的40株白念珠菌与来自HIV(一)患者的40株白念珠菌的粘附力作了比较研究,并对两组患者相关的临床与免疫学资料进行分析。方法为将0.5ml已分离鉴定并标有~(14)C的酵母细胞悬液和0.5ml用棉签刮取下的口腔粘膜细胞悬液混合孵育后离心过
Yeast adherence to oral mucosal cells is one of the main features of its pathogenicity. Progressive decline in immune function of AIDS patients prone to opportunistic infections, of which more than 80% caused by Candida albicans. The authors compared the adhesion of 40 Candida albicans isolated from the buccal mucosa of HIV (+) patients to 40 Candida albicans from HIV (i) patients using radiometric techniques and correlated two groups of patients Clinical and immunological data for analysis. The method is that 0.5 ml of the yeast cell suspension which has been identified and labeled with ~ (14) C and 0.5 ml oral mucosal cell suspension scraped off with a cotton swab are mixed, incubated and centrifuged