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0 引言 抑制肿瘤新生血管生长可以抑制肿瘤生长 ,这是目前肿瘤治疗中新发展的治疗途径 .血管生长抑制因子是由纤溶酶原中的前四个饼环区构成的 ,具有抑制肿瘤新生血管进而达到抑制肿瘤的作用 [1 ] .研究表明 ,纤溶酶原饼环区 5 (简称 K5 ,下同 ) ,具有比血管生长抑制因子更佳
0 Introduction Inhibition of tumor neovascularization can inhibit tumor growth, which is currently a new therapeutic approach in the treatment of cancer.VEGF is composed of the first four regions of plasminogen in plasminogen, and has the ability to inhibit tumor neovascularization And thus achieve the role of tumor suppression [1] .Studies have shown that plasminogen loop region 5 (referred to as K5, the same below), has a better than angiogenesis inhibitory factor