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肝硬化并发脊髓病是本世纪60年代才被认识的。1976年起我国先后有11例报告。现将我院见到的2例报告如下:【例1】男,50岁,11年前患急性黄疸型肝炎,5年后确诊为门脉性肝硬化,1年前始出现两下肢无力,以后逐渐延及两上肢,均以右侧明显,跛行.入院检查:血压140/80毫米汞柱,面色灰暗,皮肤和巩膜无黄染,蜘蛛痣(-),肝掌(+),腹部移动性浊音(+),肝未扪及,脾肋下4～5厘米,中等硬度,无压痛,颅神经及眼底(-),四肢肌力4级,肌张力高,四肢腱反射亢进,两侧均可引出持续性踝阵挛,两侧腹壁反射消失,两侧上肢病理反射阴性,两侧 Babinski氏征及 Chaddock 氏征阳性,Kernig 氏征及 Lasèque 氏征阴性,全身痛温觉、音叉觉及关节位置觉均正常。血总胆红素1.3毫克%,麝絮+++,GPT 正常,白蛋白/球蛋白为2.1克%/3.48克%,血氨128微克%,脑电图、脑扫描、颈椎片均正常。腰穿脑压不高,奎肯氏试验通畅,脑脊液常规,生化均正常,食管钡餐示食管下段静脉曲张。诊断:门脉性肝硬化,脊髓侧索硬化综合征。经服用保肝药和利尿药、限
Cirrhosis complicated by myelopathy is only recognized in the 60s of this century. Since 1976, there have been 11 reports in our country. Now in our hospital to see the 2 cases reported as follows: [Example 1] male, 50 years old, 11 years ago suffering from acute jaundice hepatitis, five years later diagnosed with portal liver cirrhosis, two years ago, two legs appeared weakness, Later gradually extended to both upper extremities, both to the right obvious limp. Admission examination: blood pressure 140/80 mm Hg, pale, skin and sclera no yellow dye, spider nevus (-), liver palpitate (+), abdominal movement Sexual dullness (+), liver palpable, spleen ribs 4 to 5 cm, moderate hardness, no tenderness, cranial nerves and fundus (-), limb muscle strength 4, high muscle tension, limb tendon hyperreflexia, both sides of the tendon All of them can lead to persistent ankle clonus, bilateral abdominal wall reflex disappeared, both sides of the upper limb pathology reflex negative, Babinski’s sign on both sides and Chaddock’s sign positive, Kernig’s sign and Lasèque’s sign negative, Joint position feel normal. Blood total bilirubin 1.3 mg%, musk oxford +++, GPT normal, albumin / globulin was 2.1 g% / 3.48 g%, blood ammonia 128 micrograms%, EEG, brain scan, cervical vertebral films were normal. Waist through the brain pressure is not high, Kuiken’s test was unobstructed, cerebrospinal fluid routine, biochemical are normal, esophageal barium showed lower esophageal varices. Diagnosis: portal cirrhosis, myelodysplastic syndrome. After taking liver and diuretic drugs, limited