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人们一直认为高胆固醇血症和高死亡串有关,但有报道,在住院病人中低胆固醇血症却和高死亡串有关。为此,作者在美国退伍军人管理局疗养院的病人中进行了验证研究。试验对象为1984年8～12月在该疗养院的129例病人,年龄41～96岁,平均70.6岁。测定的临床指标有61项,并记录胆固醇分析后14个月内发生的病死串和发病率。统计结果:血清胆固醇<150mg/dl为14例(占总数13％),病死率63％;血清胆固醇<160mg/dl为19例(占18％),病死率52％;血清胆固醇>160g/dl者病死率仅7％。发现下列7项指标对病死率有预测意义,年龄、身体功能水平、三头肌皮褶、血球比容、体重(标准体重％)、血清血红蛋白和白蛋白。但多项回归分析的结果表明,血清胆固醇水平的预测意义最大,其次是血球比容。还分析了血清胆固
It has long been thought that hypercholesterolemia is associated with high deaths but it has been reported that hypocholesterolemia is associated with high deaths in hospitalized patients. To this end, the author conducted a validation study among patients in the U.S. Veterans Administration sanitarium. The test subjects were 129 patients in the nursing home from August to December 1984, aged 41-96 years with an average of 70.6 years. There were 61 clinical indicators measured, and the incidence of morbidities and morbidity within 14 months after the cholesterol analysis was recorded. Results: Serum cholesterol <150mg / dl was 14 cases (accounting for 13%), the case fatality rate was 63%; serum cholesterol <160mg / dl was 19 cases (18%), mortality was 52%; serum cholesterol> 160g / dl The fatality rate was only 7%. The following seven indicators were found to predict mortality, age, body function level, trichoderma skin fold, hematocrit, body weight (% body weight), serum hemoglobin and albumin. However, the results of multiple regression analysis showed that the prediction of serum cholesterol level has the greatest significance, followed by hematocrit. Also analyzed serum cholesterol