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目的观察高渗氯化钠羟乙基淀粉40注射液(霍姆)抗创伤性休克的临床疗效。方法选择临床诊断为创伤性休克的患者49例,随机分为霍姆治疗组和复方氯化钠注射液组,观察两组收缩压(SBP)、舒张压(DBP)、心率(HR)、尿量和血电解质变化。结果用药后霍姆组与复方氯化钠注射液组相比,用药前的SBP、DBP、HR、尿量及用药后15、30m in的SBP、DBP、HR、尿量的变化差异有显著性(P<0.05)。结论高渗氯化钠羟乙基淀粉40注射液有明显的抗创伤性休克疗效。
Objective To observe the clinical efficacy of hypertonic sodium chloride hydroxyethyl starch 40 injection (Homer) against traumatic shock. Methods Forty-nine patients with clinically diagnosed traumatic shock were randomly divided into two groups: control group and sodium chloride injection group. SBP, DBP, HR, Volume and blood electrolyte changes. Results Compared with compound sodium chloride injection group, SBP, DBP, HR, urine volume before treatment and SBP, DBP, HR and urine volume of 15 and 30 mins after treatment were significantly different between the two groups (P <0.05). Conclusion Hypertonic sodium chloride hydroxyethyl starch 40 injection has obvious anti-traumatic shock efficacy.