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日本科学家杉田圭吉等利用碱性蛋白酶处理,从脱脂的沙丁鱼粉制备了鱼蛋白水解产物(FPH)。然后检测了FPH对血管紧张素Ⅰ转化酶(ACE)的抑制活性,以及对自然性高血压大鼠(SHR)的降血压作用。表明浓度为0.18毫克/毫升的FPH对ACE有50％的抑制作用。而
The Japanese scientist Sugita Keiji et al. Used alkaline protease to prepare fish protein hydrolyzate (FPH) from defatted sardine meal. Then, the inhibitory activity of FPH on angiotensin-1 converting enzyme (ACE) and the hypotensive effect on spontaneous hypertensive rats (SHR) were examined. FPH at a concentration of 0.18 mg / mL showed a 50% inhibition of ACE. and