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目的了解深圳市疑似预防接种异常反应(AEFI)分布特征,评价深圳市AEFI监测系统整体运行情况。方法通过国家AEFI信息管理系统收集深圳市2011—2013年监测个案数据,采用描述性分析方法进行流行病学分析。结果深圳市2011—2013年共报告AEFI个案4 399例,报告估算发生率为11.23/10万剂至28.99/10万剂;其中一般反应3 041例(69.12%),异常反应1 097例(24.93%);监测系统个案完整率为100%;及时报告率为99.07%;需调查病例1 358例,调查率为100%,48 h内及时调查率为99.78%。结论深圳市AEFI监测系统运转良好,但需进一步提高信息化管理水平,同时配合培训和督导,以期能够进一步提高监测敏感性。
Objective To understand the distribution characteristics of suspected AEFI in Shenzhen and evaluate the overall operation of AEFI monitoring system in Shenzhen. Methods The national AEFI information management system was used to collect the monitoring data from 2011 to 2013 in Shenzhen City and the descriptive analysis method was used for epidemiological analysis. Results A total of 4 399 AEFI cases were reported in 2011-2013 in Shenzhen City. The estimated incidence rate was 11.23 / 100 000 to 28.99 / 10 000; of which, 3 041 (69.12%) were general reactions and 1 097 (24.93) were abnormal reactions %). The integrity rate of surveillance system was 100%. The timely reporting rate was 99.07%. There were 1 358 cases to be investigated, the investigation rate was 100% and the timely investigation rate was 99.78% within 48 hours. Conclusion The AEFI monitoring system in Shenzhen is working well, but the information management level needs to be further improved. At the same time, the AEFI monitoring system should cooperate with the training and supervision so as to further enhance the monitoring sensitivity.