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采用实时超声显像法与放射免疫法,对20例老年NUD患者及15例对照者进行胃液体排空时间的测定及血浆胃动素、生长抑素的检测,探讨老年NUD患者目排空运动与胃肠激素之间的关系.结果显示:老年NUD患者胃液体排空T1/2为39.00±11.65min,较对照组的29.33±7.99min明显延迟(P<0.01).老年NUD患者胃动素浓度为471.5±63.06pg/ml,生长抑素浓度为63.83±11.88pg/ml,较对照组分别下降和升高(P均<0.01).老年NUD患者胃液体排空T1/2与胃动素浓度呈负相关(r=-0.936,P<0.01),与生长抑素浓度呈正相关(r=0.942,P<0.01).表明老年NUD患者胃液体排空障碍与胃动素分泌下降及生长抑素分泌增高相关.
Using real-time ultrasound imaging and radioimmunoassay, the determination of gastric fluid emptying time, plasma motilin and somatostatin in 20 elderly patients with NUD and 15 controls were performed to investigate the effects of emptying exercise And gastrointestinal hormones.The results showed that gastric emptying T1 / 2 was 39.00 ± 11.65min in the elderly patients with NUD, which was significantly delayed than that in the control group (29.33 ± 7.99min, P <0.01) The concentration was 471.5 ± 63.06pg / ml and the somatostatin concentration was 63.83 ± 11.88pg / ml, which were significantly lower and higher than those in the control group (all P <0.01) (R = -0.936, P <0.01), and it was positively correlated with somatostatin concentration (r = 0.942, P <0.01), which indicated that the gastric emptying disorder and the decrease of motilin secretion and the growth inhibition Increased secretion of hormone related.