RAB-27 and its effector RBF,1 regulate the tethering and docking steps of DCV exocytosis in C. eleg

来源 :中国科学：生命科学英文版 | 被引量 : 0次 | 上传用户：h5531465

【摘要】

：

The molecular mechanisms by which dense core vesicles(DCVs) translocate,tether,dock and prime are poorly understood.In this study,Caenorhabditis elegans was use

【作者】

：

FENG Wan Juan LIANG Tao YU Jun

【机构】

：

CollegeofLifeScienceandTechnology,NationalLaboratoryofBiomacromolecules

【出处】

：

中国科学：生命科学英文版

【发表日期】

：

2012年3期

【关键词】

：

直流电压线虫对接 RBF 胞吐牵引荧光显微镜分子机制 exocytosis dense core vesicles RAB-3 RAB-27

【基金项目】

：

We thank Michael Krause for the KM246 strain and the （p）ida-I：：IDA-I：：GFP plasmi＆ Thomas F. J. Martin for the EG3680 strain and the （p）aex-3：：ANF：：GFP plasmid, and the Caenorhabditis Genetic Center fo

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The molecular mechanisms by which dense core vesicles(DCVs) translocate,tether,dock and prime are poorly understood.In this study,Caenorhabditis elegans was used as a model organism to study the function of Rab proteins and their effectors in DCV exocytos

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RAB-27 and its effector RBF,1 regulate the tethering and docking steps of DCV exocytosis in C. eleg

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