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1 所谓核受体 核受体是一种脂溶性配体依赖NTG转录因子,通过调控靶基因的转录过程,在个体发育中参与多种生理功能的调节,如形态发育、细胞增殖分化、机体稳态维持及高级神经功能控制等。这些核受体与“未定配体的核内孤儿受体(orphanreceptor)”组成结构类似的一个受体家族。
1 The so-called nuclear receptor nuclear receptor is a fat-soluble ligand dependent NTG transcription factor, through the regulation of target gene transcription process, in the individual development involved in the regulation of a variety of physiological functions, such as morphological development, cell proliferation and differentiation, body stability State maintenance and advanced neurological function control. These nuclear receptors have a family of receptors similar in structure to the “orphanreceptors” in the nucleus of an undetermined ligand.