关于现代胚胎移植导管与妊娠结局的前瞻性随机试验

来源 :世界核心医学期刊文摘(妇产科学分册) | 被引量 : 0次 | 上传用户:wwb518
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Objective: Embryo transfer (ET) is the final crucial step in IVF treatment. The type of catheter used can affect the pregnancy rate (PR). In this prospective, randomized trial we compared the clinical PR between the Wallace and the Cook K-Jet embryo transfer catheters. Design: Prospective, randomized clinical trial. Setting: A National Health Service Assisted Reproduction Unit. Patient(s): One hundred fifty women undergoing a fresh ET. Age more than 40 years, a high basal FSH, a previous difficult ET, or more than six previous ETs were the exclusion criteria. Intervention(s): Women undergoing a fresh ET were randomized at the time of ET to either the Cook K-Jet or Wallace embryo transfer catheter. The randomization was stratified according to age and the number of previous ETs. Main Outcome Measure(s): Clinical PR. Result(s): There was no significant difference in the clinical PR between the Wallace and the Cook catheters (22/75 [29.3%] and 23/75 [30.6%], relative risk [RR]: 0.96 [95%confidence interval 0.58-1.58]). Conclusion(s): There is no significant difference in the PRs achieved by modern, soft, double-lumen ET catheters. The type of catheter used can affect the pregnancy rate (PR). In this prospective, randomized trial we compared the clinical PR between the Wallace and the Cook K-Jet Setting: A National Health Service Assisted Reproduction Unit. Patient (s): One hundred fifty women undergoing a fresh ET. Age more than 40 years, a high basal FSH, a previous difficult ET, or more than six previous ETs were the exclusion criteria. Intervention (s): Women undergoing a fresh ET were randomized at the time of ET to either the Cook K-Jet or Wallace embryo transfer catheter. The randomization was stratified according to age The number of previous ETs. Main Outcome Measure (s): Clinical PR. Result (s): There was no significant difference in the clinical PR between the Wallace and the Cook catheters (22/75 [29.3%] and 23/75 [30.6%], relative risk [RR]: 0.96 [95% c onfidence interval 0.58-1.58]). Conclusion (s): There is no significant difference in the PRs achieved by modern, soft, double-lumen ET catheters.
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