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本文以20名消化系统疾病病人和111名3～6岁健康幼儿为对象,检测眼结膜印迹细胞变化,并与血清维生素A浓度、维生素A相对剂量反应(RDR)进行比较,结果90％印迹细胞正常的病人血清维生素A浓度>0.7μmol/L,70％印迹细胞异常的病人血清维生素A浓度≤0.70μmol/L,经统计学处理,差异有极显著性意义(P<0.01);111名幼儿中有97.5％印迹细胞正常者的血清维生素A浓度>1.05μmol/L,64.2％印迹细胞异常者的血清维生素A≤1.05μmol/L,差异有极显著性意义(P<0.01)。故认为眼结膜印迹细胞法是一项简便,快速,有效的评价机体维生素A营养状况的指标,适合基层推广应用。
In this study, 20 patients with digestive diseases and 111 healthy children aged 3 to 6 years were enrolled in this study. The changes of conjunctival imprinted cells were examined and compared with serum vitamin A concentration and relative dose response (RDR) of vitamin A, and 90% of imprinted cells The serum concentration of vitamin A in normal patients was> 0.7μmol / L, the serum concentration of vitamin A in 70% of imprinted cells was ≤0.70μmol / L, the difference was statistically significant (P <0.01); 111 children Serum vitamin A concentration was 1.05μmol / L in 97.5% of normal imprinted cells, and serum vitamin A was less than or equal to 1.05μmol / L in 64.2% of imprinted cells. The difference was significant (P <0.01). Therefore, conjunctival imprinting cell method is a simple, rapid and effective evaluation of the body’s nutritional status indicators of vitamin A, suitable for grass-roots promotion and application.