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作者在猪的心肌缺血模型上发现，硝苯吡啶可使缺血所致的Ｔ波倒置迅速恢复直立。麻醉在体猪心，缩窄左冠状动脉前时间支（ＬＡＤ）至冠脉内压４．６７ｋＰａ，经ＬＡＤ插管分别输入腺苷或硝苯吡啶，在持续９分钟缺血期间，两组间的心率、左心室舒张末压、左心室发展压、冠脉流量、冠脉灌注压皆相似，且腺苷组的冠脉流量还略高。但腺苷并未使缺血所致的Ｔ波倒置改善，而硝苯吡啶却使倒置的Ｔ波迅速恢复直立，作者并对该改变的相关因素和机理进行了讨论。
The authors found in the model of myocardial ischemia in pigs, nifedipine can reverse the T wave caused by ischemia quickly restored erect. Anesthesia in vivo pig heart, narrowing the anterior branch of left anterior descending artery (LAD) to coronary pressure 4.67kPa, adenosine or nifedipine were administered via LAD intubation, respectively. During the 9-minute ischemia period, Heart rate, left ventricular end-diastolic pressure, left ventricular development pressure, coronary flow, coronary perfusion pressure were similar, and adenosine coronary flow was slightly higher. However, adenosine did not improve ischemic T wave inversion, while nifedipine reversed inverted T wave rapidly and upright. The authors also discussed the relevant factors and mechanism of the change.