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Mg~(2+)是一种有多种生理功能的无机离子。正常人血清Mg~(2+)水平为18—30μg/ml。过量Mg~(2+)具有镇静、抗惊厥及舒张外周血管、引起血压下降的作用。临床应用硫酸镁治疗先兆子痫及子痫、惊厥、高血压危象及洋地黄引起的室性早搏。但血清Mg~(2+)的安全有效范围较窄;血镁过高可引起呼吸抑制,血压剧降,甚至使心脏停跳。因此,血镁的临床监测很有必要。仪器与试药 1、日本岛津UV-120-02紫外可见光分光光度计。 2 Mg~(2+)标准溶液:9.76μg/ml配制用MgSO_4·7H_2O标准品系西安化学试剂厂生产批号720620。 3、0.1％PEG溶液:称取pEG(聚乙二醇,分子量6000)0.1g,加入50℃左右的蒸馏水溶解,冷至室温后,再加馏留水至100ml。于塑料瓶中保存。
Mg ~ (2+) is a kind of inorganic ions with a variety of physiological functions. Normal human serum Mg ~ (2+) levels of 18-30μg / ml. Excess Mg ~ (2+) has sedative, anticonvulsant and diastolic peripheral blood vessels, causing the effect of blood pressure drop. Clinical application of magnesium sulfate in the treatment of preeclampsia and eclampsia, convulsions, hypertensive crisis and digitalis premature ventricular contractions. However, the safe and effective range of serum Mg ~ (2+) is relatively narrow; hypermagnesemia can cause respiratory depression, sharp drop in blood pressure and even cardiac arrest. Therefore, the clinical monitoring of blood magnesium is necessary. Instruments and reagents 1, Japan Shimadzu UV-120-02 UV-visible spectrophotometer. 2 Mg ~ (2+) standard solution: 9.76μg / ml The preparation of MgSO_4 · 7H_2O standard line Xi’an Chemical Reagent Factory production lot 720620. 3,0.1% PEG solution: Weigh pEG (polyethylene glycol, molecular weight 6000) 0.1g, was added about 50 ℃ dissolved in distilled water, cooled to room temperature, coupled with distilled water to 100ml. Store in plastic bottle.