【摘 要】
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Because diffuse axonal injury(DAI)lacks specific clinical manifestations,it is difficult to evaluate DAI using computer tomography or conventional magnetic reso
【机 构】
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Department of Neurosurgery,First Affiliated Hospital of Chongqing Medical University,Chongqing 40001
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Because diffuse axonal injury(DAI)lacks specific clinical manifestations,it is difficult to evaluate DAI using computer tomography or conventional magnetic resonance imaging(MRI).This study investigated the value of magnetic resonance techniques using fluid-attenuated inversion recovery(FLAIR)and proton magnetic resonance spectroscopy(1HMRS)for diagnosing DAI.The corpus callosum and basal nuclei were analyzed using morphological and functional imaging.Similar to the DAI group,the non-typical DAI group exhibited similar lesion characteristics on FLAIR,as well as post-injury neurochemical and molecular changes in the corpus callosum,as detected by 1HMRS.However,there were differences in degree and severity of injury.Compared to conventional MRI,FLAIR significantly increased lesion detection.1HMRS determined biochemical metabolism changes in midline structures following DAI,which resulted in increased diagnosis of non-typical DAI,which displayed similar lesion distribution,morphology,and function as DAI.Thus,the experiment proved the value of FLAIR and 1HMRS in non-typical DAI.
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