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急性肺动脉栓塞(APE)临床表现复杂,病死率高。准确地识别高危患者,及时地应用溶栓药物或血管成形术是肺栓塞治疗中极为重要的问题。APE时的生物学指标,包括肌钙蛋白,脑钠肽,尿酸等被认为是除了临床表现、心电图和超声心动之外对APE进行危险分层的重要指标。本文就近年这方面的资料进行了归纳和总结,并探讨联合使用这些指标对APE危险分层的合理方法。
Acute pulmonary embolism (APE) clinical manifestations of complex, high mortality. Accurate identification of high-risk patients, the timely application of thrombolytic drugs or angioplasty is a very important issue in the treatment of pulmonary embolism. Biological criteria for APE, including troponin, brain natriuretic peptide, and uric acid, are considered to be important markers of risk stratification of APEs in addition to clinical presentation, electrocardiogram, and echocardiography. This article summarizes the data in recent years in this area and explores the reasonable method of stratifying APE risk by using these indicators jointly.