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目的 :观察和评价纳洛酮治疗新生儿缺氧缺血性脑病的疗效。方法 :将 60例缺氧缺血性脑病患儿分为纳洛酮治疗组 3 0例和常规治疗组 (对照组 ) 3 0例 ,观察两组的临床疗效。结果 :纳洛酮治疗组、对照组总有效率分别为 93 3 3 %和 73 3 3 %,两组比较差异有显著意义 (P <0 0 5 )。结论 :对新生儿缺氧缺血性脑病患儿 ,在对症支持治疗基础上尽早使用纳洛酮治疗 ,能减轻缺氧缺血性脑损伤程度 ,提高缺氧缺血性脑病的治愈好转率
Objective: To observe and evaluate the efficacy of naloxone in neonates with hypoxic-ischemic encephalopathy. Methods: 60 children with hypoxic ischemic encephalopathy were divided into 30 cases of naloxone treatment group and 30 cases of conventional treatment group (control group), and the clinical curative effect was observed. Results: The total effective rates of naloxone group and control group were 93.3% and 73.3%, respectively. There was significant difference between the two groups (P <0.05). Conclusion: In neonates with hypoxic-ischemic encephalopathy, symptomatic and supportive treatment based on the early use of naloxone treatment can reduce the degree of hypoxic-ischemic brain damage and improve the cure rate of hypoxic-ischemic encephalopathy