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目的探讨雷公藤多甙联合他巴唑、强的松治疗甲亢突眼临床疗效。方法我院2005年1月—2009年1月我科治疗甲亢突眼患者98例随机分为基础治疗组48例和联合治疗组50例,进行临床疗效分析。结果联合治疗组总有效率88.00%,基础治疗组总有效率58.33%,经统计学比较两组总有效率P<0.05有显著差异性。结论应用雷公藤多甙联合他巴唑、强的松治疗甲亢突眼临床疗效确切,安全可靠,提高药物疗效,降低他巴唑、强的松剂量及加快减量或停药,是治疗甲亢突眼理想的方案。
Objective To investigate the clinical efficacy of Tripterygium wilfordii combined with methimazole and prednisone in the treatment of hyperthyroidism. Methods From January 2005 to January 2009, 98 patients with hyperthyroidism and exophthalmos in our hospital were randomly divided into basic treatment group (48 cases) and combined treatment group (50 cases), and the clinical efficacy was analyzed. Results The total effective rate was 88.00% in the combined treatment group and 58.33% in the basic treatment group. There was significant difference in the total effective rate (P <0.05) between the two groups by statistical analysis. Conclusions The application of tripterygium glycosides combined with methimazole and prednisone in the treatment of hyperthyroidism has clinical effects of being safe and reliable, improving the curative effect of drugs, lowering the dosage of methimazole and prednisone, and accelerating the reduction or stopping of the disease. Eye ideal program.