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目的 观察穿透性角膜移植及板层角膜移植术后的临床效果。方法 对2 0 0 1年11月～2 0 0 4年10月在我科行角膜移植的30 0例(30 0眼)患者进行随访,其中穿透移植2 15眼,板层移植85眼。时间为2月～3年,平均16 5月。对术后视力、排斥反应、原发病复发情况及继发青光眼进行观察对比。结果 穿透移植术后视力比术前显著提高,有显著性差异,P <0.0 1。植片排斥反应2 8眼(13 .0 2 % ) ,原发病复发7眼(3 2 6 % ) ,继发青光眼32眼(14 . 88% )。板层角膜移植术后视力与术前相比无明显提高,差异无显著性,P >0 .0 5。植片排斥反应5眼(5. 88% ) ,原发病复发2眼(2 . 35 % ) ,继发青光眼0眼。结论 穿透性角膜移植较板层移植视力提高显著,但继发性青光眼的发生率也明显增高
Objective To observe the clinical effects of penetrating keratoplasty and lamellar keratoplasty. Methods Thirty (30 0 eyes) patients with corneal transplantation in our department from November 2001 to October 2004 were followed up. Among them, there were 215 penetrating transplants and 85 lamellar transplants. Time is from February to 3 years, an average of 16 May. Postoperative visual acuity, rejection, recurrence of primary disease and secondary glaucoma were observed and compared. Results The visual acuity after penetrating transplantation was significantly higher than that before operation, with significant difference (P <0.01). There were 28 eyes (23.0%) of the allograft rejection, 7 eyes (36%) of primary recurrent disease and 32 eyes (14.88%) of secondary glaucoma. Visual acuity after lamellar keratoplasty compared with preoperative no significant improvement, the difference was not significant, P> 0.05. There were 5 eyes (5.88%) of allograft rejection, 2 eyes (2.35%) of primary recurrence and 0 eyes of secondary glaucoma. Conclusions Penetrating keratoplasty has a significant improvement of visual acuity compared with lamellar transplants, but the incidence of secondary glaucoma is also significantly higher