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流行病学研究显示激素替代治疗 (ＨＲＴ)可显著减少绝经后妇女心血管疾病危险 ,但作用机制还不十分清楚。高尿酸血症是妇女缺血性心脏病死亡率独立预测因素 ,因此雌激素心血管保护作用 ,可能部分与其改变血清尿酸浓度有关。本研究旨在调查绝经后妇女ＨＲＴ对血清尿酸浓度的影响
Epidemiological studies have shown that hormone replacement therapy (HRT) can significantly reduce the risk of cardiovascular disease in postmenopausal women, but the mechanism of action is not yet clear. Hyperuricemia is an independent predictor of mortality in women with ischemic heart disease and therefore the cardiovascular protective effect of estrogen may be partly related to its change in serum uric acid concentration. The aim of this study was to investigate the effect of HRT on serum uric acid levels in postmenopausal women