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人端粒酶RNA组分(human telomerase RNA component,hTERC)基因是端粒酶的组成成分之一,其作用是作为端粒酶延长的RNA模板。鳞状上皮内瘤变是指鳞状上皮结构和细胞的异常,属于癌前病变,而子宫颈和食管是发生鳞状上皮内瘤变最常见的部位。子宫颈癌是全球第二大妇科恶性肿瘤,具有发病率高、死亡率高和年轻化的趋势[1],其中鳞状细胞癌占80%～85%。食管鳞状细胞癌是消化道常见肿瘤,
The human telomerase RNA component (hTERC) gene is one of the components of telomerase, which acts as a telomerase-extended RNA template. Squamous intraepithelial neoplasia refers to the squamous epithelial structure and cell abnormalities, belong to precancerous lesions, and cervical and esophageal squamous intraepithelial neoplasia occurs the most common site. Cervical cancer is the second largest gynecological malignancy in the world with the trend of high incidence, high mortality and rejuvenation [1]. Among them, squamous cell carcinoma accounts for 80% ~ 85%. Esophageal squamous cell carcinoma is a common tumor of the digestive tract,