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神经退行病是脑特定区域由于进展性脑神经功能不全或死亡而产生的疾病,这种脑神经恶化在临床症状发作前早已发生,如柏金森氏症(PD)在临床发病时,脑黑质多巴胺神经元已失去80%。神经退行病中最常见的有老年痴呆症(AD),柏金森氏症(PD),肌萎缩侧索硬化症(ALS),亨廷顿氏症(HD)等。老年痴呆症(Alzheimer’s disease)(AD)是一种慢性,难以治愈,持续进展的中枢神经退行病,疾病进展缓慢,逐步丧失记忆,个性变化,性格异常,思考能力下降,这些变化与脑特殊类型细胞死亡有关,大部分AD发病年龄超过60岁,早期发病除上述症状外,之后会忘记如何去做简单的动作如洗手等,随后失去所有推理能力,生活需要依赖他人,最后病人卧床不起,在发病8-12年后,死於并发症如肺炎等。
Neurodegenerative diseases are diseases that occur in specific regions of the brain due to progressive cranial nerve insufficiency or death that precede the onset of clinical symptoms such as Parkinson’s disease (PD) Dopamine neurons have lost 80%. The most common neurodegenerative diseases are Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD) and so on. Alzheimer’s disease (AD) is a chronic, refractory and persistent central nervous system degenerative disorder with slow progression of disease, progressive loss of memory, personality change, abnormal personality, and diminished ability to think, which are associated with changes in brain specific types Cell death, most of the AD onset age over 60 years of age, in addition to the above symptoms of early onset, then forget how to do simple actions such as hand-washing, and then lost all reasoning ability, life depends on others, the last patient bedridden, After the onset of 8-12 years, died of complications such as pneumonia.