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目的 检测多·克·福种衣剂经皮肤接触的亚急性毒性反应。方法 Wistar大鼠经皮染毒 ,剂量为 2 15 ,86 ,4 3mg/kg。观察体重、血常规及血液生化指标、脏体比值的变化。结果 高、中剂量组体重明显低于对照组。高剂量组白细胞总数明显高于对照组。结论 经皮接触多·克·福种衣剂对大鼠机体会产生一定损害。
Objective To examine the subacute toxicities of transdermal contact of Dick Ke Fu Seed Coatings. Methods Wistar rats were transdermally treated with 2 15, 86 and 43 mg / kg. Body weight, blood and blood biochemical indicators, the ratio of dirty body changes. Results The body weight of high and middle dose groups was significantly lower than that of the control group. The total number of high-dose white blood cells was significantly higher than the control group. Conclusion Percutaneous contact with multi-grams Fu seed coating on the body of the rat will have some damage.