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皮肤结节病对外用或损害内注射皮质类固醇疗效常不佳,但用中等或至大剂量口服则有效.磷酸氯喹曾成功地用于治疗肺皮肤结节病和与之有关的高钙血症.为了避免系统使用皮质类固醇,作者试用羟氯喹治疗了17例皮肤结节病的患者.其中女15例,男2例.年龄24～66岁.患者均有活动性皮肤损害.其中8例合并肺、眼和肝脏受累.所有病人均因局部外用、损害内注射和系统应用皮质类固醇反应不佳而改用羟氯喹口服,剂量为2～3mg/
Skin sarcoidosis is often poorly effective on topical or damaging intra-corticosteroid injections, but is effective at moderate or high doses orally, chloroquine phosphate has been successfully used to treat pulmonary skin sarcoidosis and its associated hypercalcemia In order to avoid the systematic use of corticosteroids, the authors tried hydroxychloroquine to treat 17 patients with cutaneous sarcoidosis, including 15 females and 2 females, aged from 24 to 66. All patients had active skin lesions and 8 of them were complicated Pulmonary, ocular and hepatic involvement.All patients were treated with hydroxychloroquine orally at a dose of 2 ~ 3 mg / kg due to topical external application, damage to the internal injection and systemic corticosteroid reaction.