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[目的]探讨逆向调强计划中改变射野等中心位置对剂量分布的影响。[方法]收集2007年12月至2010年12月在我院治疗的T1N0M0鼻咽癌患者7例,每例患者行CT模拟定位,设计等中心位置不同的两种治疗方案,方案A的等中心位置在靶区中心正常组织,方案B的等中心位置在靶区上部,授予靶区处方剂量及限制剂量,逆向调强计划系统优化并计算,分析两种方案之间剂量差异。[结果]方案B中晶体的剂量明显较方案A小(P<0.05),其它器官差异不明显。[结论]在一些特殊病例中,可以利用改变射野等中心位置的方法来改善剂量的分布,满足处方剂量的要求。
[Objective] The purpose of this study was to investigate the effect of changing the center position of the radiation field on the dose distribution in the reverse power plan. [Methods] Totally 7 patients with T1N0M0 nasopharyngeal carcinoma treated in our hospital from December 2007 to December 2010 were collected. Each patient underwent CT simulation of positioning and design of two treatment plans with different center positions. The center of target area is normal tissue, the center of solution B is located in the upper part of the target area, the prescription dose and the limit dose are awarded to the target area, and the reverse osmosis planning system is optimized and calculated. The dose difference between the two schemes is analyzed. [Result] The dose of crystal in scheme B was obviously smaller than that of scheme A (P <0.05), but the difference of other organs was not obvious. [Conclusion] In some special cases, the distribution of dose can be improved by changing the center of the field and so on to meet the prescription dose requirements.