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选择合适的模型体系研究主-客体相互作用有助于从分子水平上揭示生命过程中复杂的化学反应.环糊精和冠醚是研究较多的主体化合物和模拟酶.环糊精具有一个疏水性穴腔和亲水性外壳;而冠醚则有亲水性穴腔和亲油性外缘.杯芳烃是近年来发现的一种新型主体化合物,它能与多种金属离子、有机分子和离子形成主-客体包合物,被称之为继环糊精和冠醚之后的第三代主体化合物.但由于杯芳烃的水溶性很差,限制了对它们的研究和应用.为了制得水溶性杯芳烃,许多作者将羧基、磺酸基或胺基引入杯芳烃,但上述杯芳烃衍生物
Choosing a suitable model system to study host-guest interactions helps to reveal the complex chemical reactions at the molecular level during life.Cyclodextrins and crown ethers are more studied host compounds and mimic enzymes.Cyclodextrins have a hydrophobic Cavities and hydrophilic shells, while crown ethers have hydrophilic cavities and oleophilic rims.Calixarenes are new host compounds discovered in recent years and can form with many kinds of metal ions, organic molecules and ions Host-guest inclusion complex, which is called the third generation of host compounds after cyclodextrin and crown ether, but due to the poor water solubility of calixarene, which limits their research and application.In order to obtain water-soluble Calixarenes, many authors introduce carboxylate, sulfonate or amine groups into calixarenes, but the above calixarene derivatives