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本文报告了用小鼠骨髓红细胞微核和精原细胞染色体畸变分析方法来评价辐照葡萄糖对体细胞和生殖细胞的潜在致突变性及具体的研究方法,即将D-葡萄糖粉装入聚乙烯袋中,于室温下用~(60)Co源,剂量为56～58Gy/分照射(照射剂量用含铁硫酸盐放射计量仪测定),在所有实验中使用随意饲养的Swiss小鼠。微核试验:用7～8周龄Swiss小鼠,两次间隔24小时经口喂以辐照和未辐照的10%葡萄糖溶液2 ml,辐照水平的选择考虑到通常的碳水化合物的灭菌剂量,约20 kGy,本实
This paper reports the potential mutagenicity of irradiated glucose on somatic cells and germ cells using the method of chromosomal aberration analysis of mouse bone marrow erythrocyte micronuclei and spermatogonia and the specific research methods, that is, D-glucose powder into polyethylene bags , Irradiated with a ~ (60) Co source at a dose of 56 to 58 Gy / min at room temperature (irradiation dose was measured with an iron-containing sulfate radiometer), and Swiss mice were randomly fed in all experiments. Micronucleus test: Swiss mice aged 7-8 weeks were fed with 2 ml of irradiated and unirradiated 10% dextrose solution 24 hours apart at intervals of 24 hours. The level of irradiation was chosen taking into account the usual carbohydrate extinction Bacterial dose, about 20 kGy, the reality