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目的探讨中西医结合治疗抑郁症的疗效和不良反应。方法选择符合中国精神疾病分类方案与诊断标准(第3版)(CCMD-3)抑郁症诊断标准的77例病人,Hamilton抑郁量表(HAMD)17项≥18分。随机分为两组,研究组:服中药汤剂加国产阿米替林口服,共36例;对照组:单用阿米替林口服,共41例。治疗6周末进行临床疗效和HAMD量表评定。结果研究组疗效肯定,显效率为80.53%,对照组为78.05%;研究组比对照组见效快约1周;不良反应相似,均较轻微,无一例因副作用严重而中途停药者。结论运用中西医结合方法治疗抑郁症有效安全,有广阔的应用前景。
Objective To investigate the curative effect and adverse reactions of the combination of traditional Chinese and western medicine in the treatment of depression. Methods A total of 77 patients with diagnostic criteria of depression in Chinese Mental Illness Program and Diagnostic Criteria (3rd Edition) (CCMD-3) were enrolled, and 17 of 17 subjects with Hamilton Depression Scale (HAMD) ≥ 18 points. A total of 36 cases were randomly divided into two groups. The study group consisted of 36 Chinese herbal decoctions and domestic amitriptyline. In the control group, 41 cases were treated with amitriptyline alone. After 6 weeks of treatment, the clinical efficacy and HAMD scale were evaluated. Results The study group affirmed the curative effect, the effective rate was 80.53%, the control group was 78.05%. The study group was faster than the control group about 1 week; similar adverse reactions were mild, no one due to serious side effects and discontinuation. Conclusion The combination of Chinese and Western medicine treatment of depression is effective and safe, has broad application prospects.