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目的探讨深圳市福田区成人产毒株幽门螺杆菌(Hp)感染的易感因素。方法采用整群随机抽样的方法对来医院管辖的社康中心体检成人共1164名进行问卷调查,并进行Hp抗体谱检测。结果福田区成人Hp和产毒株Hp感染率分别为45.5%、14.2%,男性为46.3%、14.8%,女性为44.7%1、3.4%;<60岁年龄组Hp和产毒株Hp感染率随年龄增长而升高,>60岁感染率有所下降;Hp和产毒株Hp感染率已婚者高于未婚者;工人、农民和医师高于职员和其他职业;饮用生水者高于饮用开水者;行血清学检查前1月内服用抗菌药物者低于未服用抗菌药物者;有消化性溃疡病史者高于无消化性溃疡病史者;人均住房面积<6 m2者高于人均住房面积>6 m2者。结论深圳市福田区成人Hp和产毒株Hp感染率较低,与年龄呈正相关,与性别无关;生活条件、经济收入、文化水平及居住密度等社会环境因素影响Hp感染;Hp的传播途径尚不明确,水可能是一重要传播媒介。
Objective To investigate the predisposing factors of Helicobacter pylori (Hp) infection in adult-producing strains in Futian District, Shenzhen. Methods A total of 1164 adults from the community health centers under the jurisdiction of the hospital were surveyed by cluster random sampling and Hp antibody profiling was performed. Results The infection rates of Hp and Hp in adults in Futian District were 45.5% and 14.2% respectively, 46.3% and 14.8% in males and 44.7% and 1.4% in females respectively. Infection rates of Hp and Hp in <60 years old group The prevalence of Hp and Hp infection was higher in married people than in unmarried people; workers, peasants and doctors were higher than those in staffs and other occupations; those who had drinking water were higher than Drinking water boilers; serum serology before taking antimicrobial agents within 1 month were less than those who did not take antimicrobial drugs; a history of peptic ulcer patients with no history of peptic ulcer; per capita housing area <6 m2 were higher than the average per capita housing Area> 6 m2. Conclusions The infection rate of Hp and Hp in adult was lower in Futian District of Shenzhen City, which was positively correlated with age and had no relation with gender. Social environment factors such as living conditions, economic income, cultural level and residential density affected Hp infection. Not clear, water may be an important medium.