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目的:探讨心源性休克患者联合应用多巴胺与去甲肾上腺素治疗的临床效果。方法:采用回顾性分析的方法对我院2014年7月至2016年7月收治的78例心源性休克患者的临床资料进行研究,将入组的患者依据随机抽签原则分为对照组和研究组,每组39例,对照组患者单用多巴胺治疗,研究组患者在对照组的基础上联合应用去甲肾上腺素治疗,比较两组患者的临床疗效及治疗前后各指标变化。结果:研究组及对照组治疗总有效率分别为92.31%、74.36%,两组比较差异性显著(P<0.05),治疗后研究组患者心率、血压及心脏指数改善程度显著优于对照组,两组比较差异性显著(P<0.05)。结论:多巴胺与去甲肾上腺素联合应用能有效提高心源性休克的治疗效果,疗效安全可靠,值得临床推广应用。
Objective: To investigate the clinical effect of combination of dopamine and norepinephrine in patients with cardiogenic shock. Methods: The clinical data of 78 patients with cardiogenic shock admitted to our hospital from July 2014 to July 2016 were retrospectively analyzed. The patients were divided into control group and study according to random sampling principle Group, 39 cases in each group. Patients in the control group were treated with dopamine only. The study group was treated with norepinephrine combined with the control group. The clinical efficacy and changes of each index before and after treatment were compared between the two groups. Results: The total effective rates of study group and control group were 92.31% and 74.36%, respectively. There was significant difference between the two groups (P <0.05). After treatment, the improvement rate of heart rate, blood pressure and cardiac index were significantly better in the study group than in the control group, The difference between the two groups was significant (P <0.05). Conclusion: The combination of dopamine and norepinephrine can effectively improve the therapeutic effect of cardiogenic shock, and the curative effect is safe and reliable, which is worthy of clinical application.