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本文研究以SK-C-02苯乙烯型大孔吸附剂,从发酵滤液中提取头孢菌素C的工艺条件,包括溶液pH、流速、吸附柱高径北、解吸剂以及该吸附剂的吸附选择性与吸附能力的稳定性。结果表明SK—C—02于酸性条件下吸附,用少量低浓度的有机溶媒就能解吸完全,吸附解吸收率达到90%以上,而且对头抱菌素C和脱乙酰头孢菌素具有良好的分离能力。
In this paper, with the SK-C-02 styrene macroporous adsorbent, the process conditions for the extraction of cephalosporin C from the fermentation filtrate, including the pH of the solution, the flow rate, the northern diameter of the adsorption column, desorbent and the adsorption of the adsorbent Sexual and adsorption stability. The results showed that SK-C-02 was adsorbed under acidic conditions, with a small amount of low concentration of organic solvent can be completely desorbed adsorption desorption rate of 90% or more, and the cephalosporin C and cephalosporins have a good separation ability.