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目的：探讨ＡｐｏＡ－Ⅰ、ＡｐｏＢ与血清锌之间的关系。方法：收集８９份４５～６０岁健康体检干部的血清标本，用火箭免疫电泳法测定血清ＡｐｏＡ－Ⅰ和ＡｐｏＢ，用火焰原子吸收法测定血清锌的含量。结果：血清中锌元素含量与ＡｐｏＡ－Ｉ、ＡｐｏＢ之间的联系不具显著性（Ｐ＞０．０５）；ＡｐｏＡ－Ｉ／ＡｐｏＢ比值异常组血清锌含量高于ＡｐｏＡ－Ｉ／ＡｐｏＢ正常组（Ｐ＜０．００１）。结论：降低体内锌含量可增大ＡｐｏＡ－Ｉ／ＡｐｏＢ比值，这对预防动脉粥样硬化、心脑血管等疾病的发生有重要的临床意义
Objective: To investigate the relationship between ApoA-Ⅰ, ApoB and serum zinc. Methods: Serum samples of 89 healthy cadres aged 45-60 years were collected, serum ApoA-Ⅰ and ApoB were determined by rocket immunoelectrophoresis, and serum zinc was determined by flame atomic absorption spectrometry. Results: There was no significant correlation between serum Zinc levels and ApoA-I and ApoB (P> 0.05). Serum Zinc levels were higher in patients with abnormal ApoA-I / ApoB ratio than those in ApoA-I / ApoB <0.001). Conclusion: Decreasing the zinc content in the body can increase the ApoA-I / ApoB ratio, which has important clinical significance in preventing the occurrence of atherosclerosis, cardiovascular and cerebrovascular diseases