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为了开发能对恶性疟原虫红细胞内期抗原产生保护性抗体的DNA疫苗,本实验选用夜猴为模型进行编码尤氏疟原虫环子孢子蛋白(PyCSP)DNA疫苗免疫后最佳抗体应答的研究。
In order to develop a DNA vaccine capable of producing protective antibodies against Plasmodium falciparum erythrocytic stage end stage antigens, we used a model of a nocturnal monkey to study the optimal antibody response after immunization with Plasmodium yoelii circumsporozoite protein (PyCSP) DNA vaccine.