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目的探讨影响新生儿脐血IgE阳性值的相关因素。方法对临产孕妇进行问卷调查及血清25-羟维生素D3检测,并采集脐血检测IgE,跟踪新生儿记录出生情况,对影响脐血IgE的相关因素进行分析。结果母亲有过敏性疾病史(OR=1.65,95%CI:1.05～2.57)、出生时为巨大儿体重(OR=3.36,95%CI:1.93～5.88)、男孩(OR=1.90,95%CI:1.29～2.81)和出生时有窒息史(OR=2.88,95%CI:1.00～7.87)等4项因素是脐血IgE阳性的独立危险因素。结论脐血IgE阳性,除了出生性别和母亲有过敏史外,还与出生时窒息及巨大儿有关,应重视与此有关的孕期保健。
Objective To explore the related factors that affect the IgE positive value of neonatal cord blood. Methods Questionnaire investigation and serum 25-hydroxyvitamin D3 test were performed on pregnant women with abortion, and cord blood was collected to detect IgE. The neonatal records of birth and birth were analyzed. The related factors affecting IgE in cord blood were analyzed. Results The mothers had a history of allergic diseases (OR = 1.65, 95% CI: 1.05-2.57), with a very significant weight at birth (OR = 3.36,95% CI: 1.93-5.88) : 1.29-2.81) and history of asphyxia at birth (OR = 2.88,95% CI: 1.00-7.87) were independent risk factors for IgE positive in cord blood. Conclusion IgE positive cord blood, in addition to birth and maternal history of allergy, but also with the birth of asphyxia and macrosomia, should pay attention to the health care during pregnancy.