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76例高血压合并糖尿病患者随机分为治疗组40例,给予硫酸镁静脉滴注,对照组36例给予依那普利口服。治疗前后检测全血粘度低切、全血粘度高切、血浆粘度、血沉、纤维蛋白原等血流变学指标。结果:硫酸镁治疗组血流变学指标明显改善,依那普利组无明显改善。结论;硫酸镁可能对高血压合并糖尿病血管并发症有预防和治疗作用。
76 patients with hypertension and diabetes mellitus were randomly divided into treatment group 40 cases, given intravenous infusion of magnesium sulfate, 36 cases in the control group were given enalapril orally. Low-cut whole blood viscosity, high viscosity cut, plasma viscosity, erythrocyte sedimentation rate and fibrinogen were measured before and after treatment. Results: The indexes of hemorheology were significantly improved in the magnesium sulfate treatment group, but no significant improvement was found in the enalapril group. Conclusion: Magnesium sulfate may prevent and treat hypertension complicated with vascular complications of diabetes.