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目的:探讨重症肺炎合并癫痫患儿的治疗方案。方法:根据抗癫痫药物的药物代谢动力学特点,结合临床药师参与重症肺炎合并癫痫患儿的实际案例,对药物合理应用进行分析和阐述。结果:重症肺炎合并癫痫患儿的药学监护重点在于抗菌药物的选择及其对抗癫痫药物的影响,通过制定合理的个体化给药方案及用药监护,能达到安全、有效的抗癫痫和抗感染治疗效果。结论:临床药师参与制定个体化给药方案,可避免药物间相互作用发生,提高医疗质量。
Objective: To explore the treatment of severe pneumonia complicated with epilepsy in children. Methods: Based on the pharmacokinetic characteristics of antiepileptic drugs combined with the actual cases of clinical pharmacists involved in children with severe pneumonia complicated by epilepsy, the rational use of drugs was analyzed and elaborated. Results: The focus of pharmacy care in children with severe pneumonia complicated with epilepsy was the choice of antimicrobial agents and their effect on antiepileptic drugs. By formulating rational individualized dosing regimen and medication monitoring, safe and effective antiepileptic and anti-infective therapy could be achieved effect. Conclusion: The clinical pharmacists involved in the development of individualized drug delivery programs can avoid the occurrence of drug-drug interactions and improve the quality of medical care.