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辐射诱发染色体畸变可分为两个主要类型:互换和断裂。从分子水平看,染色体断裂的形成很可能是DNA双链断裂(dsb)不能重接的结果。目前,有关dsb不能重接及其转变成染色体断裂的准确机制还不十分清楚。一种可能的机制是dsb在重接前加上了端粒。dsb部位添...
Radiation-induced chromosomal aberrations can be divided into two main types: exchange and fragmentation. At the molecular level, the formation of chromosome breaks is likely to be the result of DNA duplex breaks (dsb) that can not be reconnected. At present, the exact mechanism by which dsb can not be reconnected and converted to chromosomal breaks is not well understood. One possible mechanism is that dsb adds telomeres before reconnection. dsb site Tim ...