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目的 :评价加替沙星治疗下呼吸道感染的临床疗效。方法 :5 6例病人随机分为治疗组 2 8例 ,加替沙星 0 .4 g静滴qd ;对照组 2 8例 ,左氧氟沙星0 .4 g静滴 qd ;疗程均为 7～ 14d。 结果 :加替沙星组和左氧氟沙星组的总有效率分别 93%和90 % ,细菌清除率为 88%和 88% ;不良反应发生率均为 7%。两组比较无显著性差异。结论 :加替沙星治疗下呼吸道感染疗效确切 ,安全性好。
Objective: To evaluate the clinical efficacy of gatifloxacin in the treatment of lower respiratory tract infection. Methods: Fifty-six patients were randomly divided into treatment group 28 cases, gatifloxacin 0.4 g intravenous qd; control group 28 cases, levofloxacin 0. 4 g intravenous qd; course of treatment were 7 to 14 days. Results: The total effective rates of gatifloxacin group and levofloxacin group were 93% and 90% respectively, the bacterial clearance rate was 88% and 88%, and the incidence of adverse reactions was 7%. There was no significant difference between the two groups. Conclusion: Gatifloxacin treatment of lower respiratory tract infection is effective and safe.