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近年来,我国中西药配伍治疗疾病,已逐渐成为临床治疗的重要手段,用中西药配伍复方制剂的种类日益增多,治疗范围也越来越广。但在临床上也有一些患者将中西药联合应用后,出现疗效降低或增加毒性的现象。所产生不良的后果,应当引起医药卫生人员的重视。现根据有关文献,将中西药联合应用中,发生在药效学上的配伍禁忌综述如下。一,药理性配伍禁忌中西药配伍时,在药理作用上产生了拮抗致使毒性或不良反应增加。茵陈与氯霉素合用:胆囊炎患者常用茵陈,西药有时用氯霉素,有人研究报道茵陈对氯霉素的抗菌性有拮抗作用,可降低甚至抵消氯霉素的疗效。甘
In recent years, the compatibility of Chinese and Western medicine treatment of diseases, has gradually become an important means of clinical treatment, with the compatibility of traditional Chinese and western medicines growing types of compounds, the treatment is also more and more widely. However, there are also some patients in clinical clinical application of Chinese and Western medicine, there is a reduction in efficacy or increase the toxicity of the phenomenon. The resulting adverse consequences should arouse the attention of medical and health personnel. Now based on the relevant literature, the joint application of Chinese and Western medicine, occurs in the pharmacodynamics compatibility taboo summarized below. First, the pharmacological compatibility of contraindications Western medicine compatibility, the pharmacological effects of antagonism resulting in increased toxicity or adverse reactions. Capillaris and chloramphenicol: caprine commonly used in patients with cholecystitis, western medicine and sometimes with chloramphenicol, some studies have reported capillaris antibacterial antagonistic effect of chloramphenicol, can reduce or even offset the efficacy of chloramphenicol. sweet