论文部分内容阅读
目的探讨标准剂量米非司酮配伍米索前列醇终止13~20周妊娠治疗中,米索前列醇阴道给药和口服给药的效果比较。方法回顾分析200例米非司酮配伍米索前列醇终止妊娠孕妇临床资料。其中米索前列醇口服给药108例,米索前列醇阴道给药92例。比较两组引产时间、引产成功率、引产后出血量及用药胃肠道及神经系统副反应。结果两组在引产时间、引产成功率及引产后出血量差异均无统计学意义(P>0.05)。两组在胃肠道及神经系统副反应差异均有统计学意义(P<0.05)。结论米非司酮配伍米索前列醇终止13~20周妊娠治疗中,米索前列醇阴道给药和口服给药的效果无显著差异,米索前列醇阴道给药较口服给药副反应小。
Objective To investigate the effect of misoprostol on vaginal administration and oral administration in standard dose mifepristone combined with misoprostol to terminate the pregnancy in 13 to 20 weeks. Methods A retrospective analysis of 200 cases of mifepristone with misoprostol termination of pregnancy in pregnant women clinical data. Among them, misoprostol was orally administered in 108 cases and misoprostol was administered vaginally in 92 cases. The time of induction of labor, the success rate of induction of labor, the amount of bleeding after induction of labor and the gastrointestinal and nervous system side effects were compared between the two groups. Results There was no significant difference between the two groups in induction of labor, success rate of induced labor and postpartum hemorrhage (P> 0.05). The two groups in the gastrointestinal and nervous system side effects were statistically significant (P <0.05). Conclusions Mifepristone combined with misoprostol stopped vaginal administration and oral administration of misoprostol in the treatment of 13 to 20 weeks of pregnancy, there was no significant difference in vaginal administration of misoprostol than oral administration of small side effects .