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T细胞介导的免疫应答在机体排斥肿瘤的过程中起核心主导作用 ,原始的CD8+ T细胞分化成效应细胞 ,在自身MHCⅠ类分子存在的条件下能识别特异性抗原肽 ,CD8+ CTL可直接识别、杀伤表达特异性抗原的肿瘤细胞。多数抗原加工通道能产生有效的CD8+ T细胞介导的免疫反应
T cell-mediated immune response plays a central role in tumor rejection. The original CD8 + T cells differentiate into effector cells that recognize specific antigenic peptides in the presence of MHC class I molecules. CD8 + CTLs can be directly identified , Killing tumor cells that express specific antigens. Most antigen-processing channels produce efficient CD8 + T cell-mediated immune responses