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白细胞介素3受体(IL-3R)在介导白细胞介素3(IL-3)的多种生物学功能中起着重要作用。由于成功地克隆出IL-3R各组分的cDNA,使得对IL-3R结构及功能的认识更加深入,为阐明IL-3的作用机制奠定了基础,本文着重介绍IL-3R结构及信号传导的研究进展。
Interleukin 3 receptor (IL-3R) plays an important role in mediating a variety of biological functions of interleukin 3 (IL-3). Because of the successful cloning of cDNA of each component of IL-3R, the understanding of the structure and function of IL-3R is further deepened, which lays the foundation for elucidation of the mechanism of action of IL-3. This article focuses on the structure and signal transduction of IL-3R Research progress.