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目的探讨老年2型糖尿病患者行运动疗法后血白细胞介素-8(IL-8)、C反应蛋白(CRP)的变化。方法对26例老年2型糖尿病患者进行运动疗法,每隔1周抽血检测IL-8、CRP。结果运动疗法1个月后,IL-8、CRP与运动前比较均显著降低(P<0.01);有效率为88%以上,显著高于对照组。对照组患者的IL-8、CRP无显著变化(P>0.05)。结论运动疗法能明显增强老年2型糖尿病患者抗炎症能力和免疫力。
Objective To investigate the changes of interleukin-8 (IL-8) and C-reactive protein (CRP) in elderly type 2 diabetic patients after exercise therapy. Methods Twenty-six elderly patients with type 2 diabetes were treated with exercise therapy. Blood was collected every other week for detection of IL-8 and CRP. Results After 1 month of exercise therapy, the levels of IL-8 and CRP were significantly lower than those before exercise (P <0.01). The effective rate was 88%, significantly higher than that of the control group. There was no significant change in IL-8 and CRP in control group (P> 0.05). Conclusion Exercise therapy can significantly enhance the anti-inflammatory ability and immunity of elderly patients with type 2 diabetes mellitus.