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目的：研究肝硬化患者腺垂体分泌细胞的储备功能。方法：用放免法测定10例男性肝硬化患者行药物腺垂体兴奋试验前后的血清PRL、GH、FSH和LH水平。结果：兴奋腺垂体前与健康对照组比较患者血清GH增高（P＜0．05）、FSH降低（P＜0．05）、LH（P＞0．05）和PRL（P＞0．05）与健康对照组比较差异无显著性，兴奋后垂体激素均值明显低于健康对照组（P值分别为，P＜0．01，P＜0．05，P＜0．05和P＜0．05），GH高峰值出现时间延迟．结论：肝硬化患者腺垂体储备功能低下．
Objective: To study the reserve function of adenohypophysis secretory cells in patients with cirrhosis. Methods: Serum PRL, GH, FSH and LH levels were measured by radioimmunoassay in 10 male patients with cirrhosis before and after drug-induced pituitary apoplexy. Results: Compared with the healthy control group, the serum GH was increased (P <0.05), FSH was decreased (P <0.05), LH (P> 0.05) Compared with the healthy control group, there was no significant difference. The mean of pituitary hormone after excitement was significantly lower than that of healthy control group (P <0.01, P <0.05, P <0.05 and P <0.05 respectively ), GH peak appears time delay. Conclusions: The pituitary reserve function is poor in cirrhotic patients.