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目的探讨胰腺癌的早期诊断、手术治疗的效果以及微创外科技术带来的新问题。方法回顾性分析1991年1月至2003年12月148例胰腺癌的外科治疗及随诊情况。结果施行手术148例,手术切除率38.5%,根治性切除率28.4%,姑息性切除率10.1%。根治性切除组1、3、5年存活率分别是52.6%、18.4%、7.9%;姑息性切除组1、3、5年存活率分别是23.1%、0、0。术后采取全身化疗。对复发或原发病变进行热疗,姑息旁路引流组1、3年存活率达到16.7%、3.3%。结论重视高危人群的监测,胰腺癌应采取以手术为主的综合治疗模式。
Objective To explore the early diagnosis of pancreatic cancer, the effect of surgical treatment and minimally invasive surgery brought new problems. Methods The surgical treatment and follow-up of 148 cases of pancreatic cancer from January 1991 to December 2003 were retrospectively analyzed. Results of the operation of 148 cases, 38.5% surgical excision, radical resection rate of 28.4%, palliative resection rate of 10.1%. The survival rates at 1, 3, and 5 years after radical resection were 52.6%, 18.4% and 7.9%, respectively. The 1, 3 and 5-year survival rates of the resection group were 23.1% and 0,0, respectively. After surgery to take systemic chemotherapy. The recurrence or primary lesions for hyperthermia, palliative bypass drainage group 1, 3-year survival rate of 16.7%, 3.3%. Conclusion Attention should be paid to the monitoring of high-risk groups. Pancreatic cancer should adopt a comprehensive surgical model.