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患者1,女,46岁,因泌尿系感染就诊治疗,给予克林霉素磷酸酯1.2 g(华北制药集团制剂有限公司,批号050701)加入0.9%氯化钠注射液250 ml,ivd qd,输液10 min 后自诉口苦,无其他不适感觉,由于患者可耐受,未停用,继续治疗。症状持续,停药30 min 后消失。第2天使用剂量、次数同第1天,症状又重复出现。未使用其他药品。患者2,女,42岁,因上呼吸道感染给予克林霉素磷酸酯0.6 g(华北制药集团制剂有限公司,批号050701)加入5%葡萄糖注射液250 ml,ivd,qd。输液过程中自诉口苦,症状同前。第2天使用时症状重复出现。同时使用药品利巴韦林注射液,维生素 B_6注射液。患者3,男,21岁,因左距骨粉碎性骨折入院就诊,予克林霉素0.9 g(华北制药集团制剂有限公司,批号050701)加入0.9%氯化钠注射液250 ml,ivd,qd。输液10 min 左右感觉口苦,可忍受。输完后约15 min 后口苦症状逐渐消失,连
Patients 1, female, 46 years old, due to treatment of urinary tract infection, given clindamycin phosphate 1.2 g (North China Pharmaceutical Group Co., Ltd., batch 050701) added 0.9% sodium chloride injection 250 ml, ivd qd, infusion After 10 min private prosecution mouth bitter, no other feeling of discomfort, due to patient tolerance, non-stop, continue treatment. The symptoms persisted and disappeared after 30 minutes of withdrawal. Day 2 dose, the same number of times with the first day, the symptoms appear again. No other drugs were used. Patient 2, female, 42 years old, clindamycin phosphate 0.6 g (North China Pharmaceutical Group Pharmaceutical Co., Ltd., lot 050701) was given 250 ml, ivd, qd of 5% glucose injection due to upper respiratory tract infection. Prosecution in the infusion process mouth bitter, symptoms with the former. Symptoms repeated on Day 2. At the same time use of drugs ribavirin injection, vitamin B_6 injection. Patient 3, male, 21 years old, was admitted to hospital for comminuted fracture of left talus. 0.9% sodium chloride injection 250 ml, ivd, qd was given to clindamycin 0.9 g (Huabei Pharmaceutical Group Co., Ltd., lot 050701). Infusion 10 min or so feel mouth bitter, can endure. After about 15 min after losing oral Miserable symptoms gradually disappear, and even