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目的:应用颈部血管彩色多普勒血流显像(color Doppler flow imaging,CDFI)和经颅多普勒超声(transcranial Doppler,TCD)随访观察颈动脉狭窄患者支架置入后颈部血管、颅内血流动力学及脑血管储备能力(cerebrovascular reserve capacity,CVR)的变化.方法:对96例颈动脉狭窄支架置入术的患者进行CDFI和TCD检查,对比治疗前与治疗后1个月、6个月、1 a及2a血流动力学变化.结果:术后颈动脉狭窄段收缩期峰值流速(peak systolic velocity,PSV)及阻力指数(resistance index,RI)低于术前,患侧大脑中动脉PSV、搏动指数(pulsatility index,PI)及CVR高于术前,P值均<0.05.治疗后1个月、6个月、1 a及2a的颈部及颅内血流检测指标之间的变化没有统计学意义;2a内随访,4例病例出现支架术后再狭窄,支架再狭窄率为4.2%.结论:颈动脉支架置入治疗可以明显改善颈动脉狭窄患者颈部血管、颅内的血供及CVR,CDFI联合TCD检查可以对颈动脉支架置入疗效及术后随访进行准确的评估.“,”Objective To apply color Doppler flow imaging (CDFI) and transcranial Doppler (TCD) to the follow-up observation of the changes of cervical vessel,intracranial hemodynamics and cerebrovascular reserve capacity (CVR) of the patients after carotid artery stent implantation.Methods Totally 96 patients with carotid artery stent implantation underwent CDFI and TCD examinations,and the changes of hemodynamics were compared before and 1 month,6 months,1 a and 2 a after implantation.Results The values of peak systolic velocity (PSV) and resistance index (RI) at the areas of carotid stenosis were lower significantly than those before implantation,while the values of PSV,pulsatility index (PI) and CVR of the middle cerebral artery were obviously higher than those before implantation (P<0.05).There were no significant differences between the cervical and intracranial hemodynamics indexes 1 month,6 months,1 a and 2 a after treatment.Two-year follow-up found 4 cases of restenoses after implantation,and the rate for restenosis was 4.2%.Conclusion Carotid artery stent implantation improves significantly cervical and intracranial blood supply as well as CVR of the carotid stenosis patient,and CDFI combined with TCD can be used for the accurate evaluation of the efficacy and postoperative follow-up of carotid artery stent implantation.